Lodonak BP - 60 Tablets
DIET SLEEP/MENTAL Depression,Anxiety,BPD Nicotine Withdraw(Nicotine Free) Naltrexone NDRIs +5

Lodonak BP

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Generic For CONTRAVE|MYSIMBA
Active Ingredient NALTREXONE|BUPROPION
Strength 8MG|90MG
Manufacturer KACHHELA MEDEX
Lodonak BP - 60 Tablets
Lodonak BP - 60 Tablets
Lodonak BP - 60 Tablets
Lodonak BP - 60 Tablets
Lodonak BP - 60 Tablets
Lodonak BP - 60 Tablets
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Product Description

Lodonak BP is a fixed-dose combination of Naltrexone 8mg and Bupropion 90mg formulated for chronic weight management. It targets multiple neurological pathways to reduce appetite, emotional eating, and cravings, while also supporting mental health. Acting on the brain’s reward system, it enhances satiety and decreases compulsive behavior, making it a powerful option for individuals struggling with obesity and mood regulation. As a generic counterpart to the FDA-approved Contrave, Lodonak BP delivers comparable efficacy with improved accessibility for long-term treatment goals.

Indications & Uses

- Sleep & Mental Health > Depression (Bupropion component) Bupropion enhances dopamine and norepinephrine activity in the brain, offering antidepressant effects without the weight gain seen with many other antidepressants, making it particularly suitable for overweight patients. - Smoking Cessation Treatment > Nicotine Withdrawal Bupropion reduces nicotine cravings and eases withdrawal symptoms, helping smokers manage anxiety, irritability, and poor concentration during cessation. It is widely used in smoking cessation protocols. - Sleep & Mental Health > ADHD Though not a first-line treatment, bupropion may support adults with ADHD by improving focus, reducing impulsivity, and addressing comorbid depressive symptoms. - Diet > Appetite Suppressants Designed to help reduce food cravings and control eating behaviors by modulating both appetite regulation and dopamine-driven reward pathways. A useful aid in clinical obesity and lifestyle-associated overeating.

Benefits & Effectiveness

Naltrexone acts as an opioid receptor antagonist, disrupting the reward feedback loop associated with compulsive eating. Bupropion, a norepinephrine-dopamine reuptake inhibitor (NDRI), improves mood and decreases appetite. Together, they create a dual-action approach that curbs hunger while addressing underlying behavioral and emotional patterns linked to obesity, smoking, or depression.

Directions for Use

Each extended-release tablet contains naltrexone 8mg and bupropion 90mg. - Week 1: 1 tablet in the morning - Week 2: 1 tablet twice daily (morning and evening) - Week 3: 2 tablets in the morning, 1 in the evening - Week 4 and beyond: 2 tablets twice daily Maximum daily dose: 4 tablets/day (naltrexone 32mg + bupropion 360mg) If no ≥5% weight loss is achieved after 12 weeks at full dose, treatment should be reconsidered. Avoid combining with other weight loss agents. Cardiovascular safety over long-term use is not fully established.

Storage

Store below 25°C in a dry place, protected from sunlight and moisture. Keep out of reach of children and do not use after expiry date.

Possible Side Effects

Common side effects include nausea, headache, insomnia, dry mouth, dizziness, and anxiety. Less frequent but serious side effects may include increased blood pressure, seizure risk, or suicidal thoughts. Seek medical attention if severe mood changes, chest pain, or hallucinations occur.

FAQs

It is used to support weight loss in adults with obesity or overweight, and also offers mood support and smoking cessation benefits.
It reduces appetite and food cravings by acting on brain pathways responsible for hunger and reward.
Yes, the bupropion component helps reduce nicotine cravings and has antidepressant effects.
If you don’t lose at least 5% of your body weight within 12 weeks, your doctor may advise discontinuation. Long-term use requires monitoring.
Avoid taking with high-fat meals and other bupropion- or naltrexone-containing products. Inform your doctor of all medications.
No. The combination with other weight loss agents is not recommended unless directed by a physician.

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