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| Generic For | LAMICTAL |
|---|---|
| Active Ingredient | LAMOTRIGINE |
| Strength | 100MG |
| Manufacturer | INTAS PHARMACEUTICALS |
| Pack Size | Price Per Unit | Unit Price | QTY | CART | Best Coupon Price MAX DISCOUNT |
|---|---|---|---|---|---|
| 1 BOX - 100 TABLETS | $ 0.63 | $ 62.90 |
$ 53.46
Apply ZARVY26 (-15%)
You save $ 9.44
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| 2 BOXES - 200 TABLETS | $ 0.66 | $ 131.90 |
$ 112.12
Apply ZARVY26 (-15%)
You save $ 19.79
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| ★ Best Value 3 BOXES - 300 TABLETS | $ 0.66 | $ 198.90 |
$ 169.07
Apply ZARVY26 (-15%)
You save $ 29.84
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Lamez 100 is a widely trusted generic formulation of lamotrigine, prescribed primarily for managing seizure disorders and mood stabilization. With well-documented efficacy and tolerability, it serves as a foundational treatment for epilepsy and bipolar depression, playing a crucial role in regulating abnormal neuronal discharges and maintaining emotional balance.
- Sleep & Mental Health > Epilepsy Lamotrigine is extensively used for controlling partial and generalized seizures. By modulating abnormal neuronal activity, it offers significant relief and long-term stability for patients with epilepsy, either as monotherapy or in combination with other anticonvulsants. > Bipolar Disorder Proven to be effective in delaying the recurrence of depressive episodes in bipolar disorder, lamotrigine is preferred as a maintenance agent. Its targeted action helps in achieving long-term emotional stability, particularly in patients with predominant depressive phases. > Depression, Anxiety, PTSD When standard antidepressants such as SSRIs and SNRIs are ineffective or poorly tolerated, lamotrigine serves as an adjunctive treatment. It contributes to mood stabilization and emotional regulation in patients with chronic anxiety or PTSD. > ADHD (Attention Deficit Hyperactivity Disorder) In children and adults with coexisting epilepsy or mood disorders, lamotrigine may be used off-label to support attention regulation and emotional balance. > Improve Memory, Concentration and Brain Function Clinical observations suggest benefits in enhancing cognitive performance, including attention, concentration, and working memory, making it a supportive option for neurological conditions beyond epilepsy.
Lamotrigine acts by inhibiting voltage-sensitive sodium channels and reducing excessive release of excitatory neurotransmitters such as glutamate. This helps stabilize neuronal membranes, suppress abnormal discharges, and regulate emotional states in mood disorders.
Adult Dose - Epilepsy (Adjunctive Therapy) • With valproate: 25 mg every other day (Week 1–2) → 25 mg daily (Week 3–4) → Maintain 100–200 mg/day • No inducers/inhibitors: 25 mg daily (Week 1–2) → 50 mg daily (Week 3–4) → Maintain 225–375 mg/day • With enzyme inducers: 50 mg daily (Week 1–2) → 100 mg daily (Week 3–4) → Maintain 300–500 mg/day - Bipolar Disorder • With valproate: Start 25 mg every other day → Titrate to 50 mg → Maintain at 100 mg/day • No inducers/inhibitors: Start at 25 mg daily → Titrate to 100 mg → Maintain at 200 mg/day • Enzyme inducers: Begin at 50 mg → Escalate to 300 mg → Maintain up to 400 mg/day - Lennox-Gastaut Syndrome • Titration mirrors epilepsy guidelines • Final dose depends on interacting drugs: - With valproate: 100–200 mg/day - No inducers/inhibitors: 225–375 mg/day - With inducers: 300–500 mg/day Pediatric Dose - Age 2–12 years • With valproate: Start at 0.15 mg/kg/day → Increase to 0.3 mg/kg/day → Titrate to 1–5 mg/kg/day (Max: 200 mg) • No inducers/inhibitors: Start at 0.3 mg/kg/day → Titrate to 4.5–7.5 mg/kg/day (Max: 300 mg) • Enzyme inducers: Start at 0.6 mg/kg/day → Titrate to 5–15 mg/kg/day (Max: 400 mg) - Age 13+ years • Follow adult XR titration schedule - Under 2 years • Not recommended - Monotherapy Conversion • From older AEDs: Slowly discontinue over 4 weeks while titrating lamotrigine to 500 mg/day • From valproate: Titrate lamotrigine while tapering valproate, achieving 500 mg/day lamotrigine monotherapy - IR to XR Conversion • Allowed as a direct switch • Monitor closely for seizure control • Adjust dose as needed, especially with enzyme inducers
Store in a cool, dry place below 25°C. Protect from direct sunlight and humidity. Keep in original packaging to prevent moisture exposure.
Common side effects include dizziness, headache, nausea, blurred vision, or sleepiness. In rare cases, serious skin reactions like Stevens-Johnson syndrome or toxic epidermal necrolysis may occur. Gradual titration is critical to minimize risks. Any allergic reactions or mood changes should prompt immediate medical attention.
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