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| Generic For | LAMICTAL |
|---|---|
| Active Ingredient | LAMOTRIGINE |
| Strength | 25MG |
| Manufacturer | INTAS PHARMACEUTICALS |
| Pack Size | Price Per Unit | Unit Price | QTY | CART | Best Coupon Price MAX DISCOUNT |
|---|---|---|---|---|---|
| 1 BOX - 100 TABLETS | $ 0.39 | $ 39.00 |
$ 33.15
Apply ZARVY26 (-15%)
You save $ 5.85
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| 2 BOXES - 200 TABLETS | $ 0.42 | $ 84.00 |
$ 71.40
Apply ZARVY26 (-15%)
You save $ 12.60
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| ★ Best Value 3 BOXES - 300 TABLETS | $ 0.41 | $ 124.00 |
$ 105.40
Apply ZARVY26 (-15%)
You save $ 18.60
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Lamez 25 is a widely prescribed antiepileptic and mood-stabilizing medication, formulated with lamotrigine 25mg. It is frequently used in the management of seizure disorders and bipolar, disorder, especially for long-term prevention of depressive episodes. The drug operates by regulating the brain's electrical signals and is often selected for its favorable side effect profile and minimal cognitive interference. Lamez 25 is also studied in off-label use for various psychiatric and neurological conditions, such as PTSD, chronic anxiety, and emotional instability in ADHD patients.
- Sleep & Mental Health > Epilepsy Lamotrigine is used to control partial-onset and generalized seizures by stabilizing neuronal electrical activity, making it a frontline choice in antiepileptic therapy. > Bipolar Disorder Effectively delays recurrence of depressive episodes in bipolar disorder, showing stronger efficacy in preventing depressive rather than manic episodes. > Depression, Anxiety, PTSD Used adjunctively to regulate mood in patients with chronic emotional instability and those intolerant to SSRIs or SNRIs. > ADHD (Attention Deficit Hyperactivity Disorder) Beneficial in cases where ADHD is comorbid with epilepsy or mood disorders. Supports emotional regulation. > Improve Memory, Concentration and Brain Function Some studies report improvements in attention, memory, and cognitive performance in neurological conditions.
Lamez 25 works by stabilizing voltage-gated sodium channels and reducing excessive glutamate release, which helps to manage abnormal electrical activity in the brain. This mechanism is effective in controlling seizures and maintaining emotional stability. It provides a balanced efficacy profile with fewer sedative or metabolic effects compared to other antiepileptic or mood stabilizers, making it suitable for long-term therapy.
Adult Dose: - Epilepsy (Adjunctive): • With valproate: 25 mg every other day (Week 1–2) → 25 mg daily (Week 3–4) → Maintain 100–200 mg/day • No enzyme inducers/inhibitors: 25 mg daily → 50 mg daily → Maintain 225–375 mg/day • With enzyme inducers: 50 mg daily → 100 mg daily → Maintain 300–500 mg/day - Bipolar Disorder: • With valproate: 25 mg every other day → 25 mg daily → 50 mg → Maintain 100 mg/day • No enzyme modifiers: 25 mg daily → 50 mg → 100 mg → Maintain 200 mg/day • With inducers: 50 mg → 100 mg → 200 mg → 300 mg → Maintain up to 400 mg/day - Lennox-Gastaut Syndrome: • Follow epilepsy dosing based on adjunctive protocol Pediatric Dose: - Age 2–12: • With valproate: Start at 0.15 mg/kg/day → Increase to 1–5 mg/kg/day (Max 200 mg/day) • No modifiers: Start at 0.3 mg/kg/day → 4.5–7.5 mg/kg/day (Max 300 mg/day) • With inducers: Start at 0.6 mg/kg/day → 5–15 mg/kg/day (Max 400 mg/day) - Age 13+: • Follow adult XR dosing per concomitant drug profile - Under 2: • Not recommended Monotherapy Conversion (≥16 years): - From carbamazepine/phenytoin/etc: Titrate lamotrigine to 500 mg/day, taper existing AED by 20% weekly - From valproate: Increase lamotrigine gradually to 200–300–500 mg/day, taper valproate in stages IR to XR Conversion: - Patients may switch directly. Monitor for seizure control. Enzyme inducers may require dose adjustments.
Store Lamez 25 in a cool, dry place at 15–30°C, away from sunlight and moisture. Keep tablets in their original packaging. Do not freeze or expose to humidity. Ensure child-resistant storage.
Common side effects include dizziness, headache, blurred vision, nausea, and fatigue. Severe reactions may involve skin rash, including life-threatening conditions like Stevens-Johnson syndrome. Risk of rash is minimized by slow dose escalation. Patients should report any allergic symptoms or skin changes immediately.
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