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Review Details
(59)
| Generic For | INDOCIN |
|---|---|
| Active Ingredient | INDOMETHACIN |
| Strength | 25MG |
| Manufacturer | JAGSONPAL PHARMACEUTICALS |
| Pack Size | Price Per Unit | Unit Price | QTY | CART | Best Coupon Price MAX DISCOUNT |
|---|---|---|---|---|---|
| 1 BOX - 300 TABLETS | $ 0.41 | $ 123.70 |
$ 105.15
Apply ZARVY26 (-15%)
You save $ 18.56
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| 2 BOXES - 600 TABLETS | $ 0.43 | $ 255.20 |
$ 216.92
Apply ZARVY26 (-15%)
You save $ 38.28
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| ★ Best Value 3 BOXES - 900 TABLETS | $ 0.44 | $ 399.80 |
$ 339.83
Apply ZARVY26 (-15%)
You save $ 59.97
|
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Indocap 25 Capsule contains indomethacin, a potent nonsteroidal anti-inflammatory drug (NSAID) that offers strong anti-inflammatory, analgesic, and antipyretic effects. It works by inhibiting cyclooxygenase (COX-1 and COX-2) enzymes, thereby blocking the production of prostaglandins responsible for pain and inflammation. Indomethacin is widely prescribed for inflammatory joint disorders such as rheumatoid arthritis, osteoarthritis, and ankylosing spondylitis, and is especially effective in acute flares of gout. It is also used for painful musculoskeletal conditions including bursitis, tendinitis, and low back pain. In neonatal care, intravenous formulations of indomethacin are used off-label to induce closure of a patent ductus arteriosus (PDA) in preterm infants. Due to its gastrointestinal toxicity profile, it is typically reserved for short-term use or cases requiring aggressive anti-inflammatory therapy.
- Painkillers & Headache > Musculoskeletal Pain Provides rapid pain relief in acute musculoskeletal injuries such as low back pain, shoulder bursitis, and tendonitis. Useful in patients requiring short-term high-intensity anti-inflammatory action. - Lifestyle-Related Diseases > Gout/Hyperuricemia First-line treatment for acute gouty arthritis flares. Reduces joint inflammation, swelling, and severe pain typically within hours of administration. > Rheumatoid Arthritis Relieves joint stiffness, swelling, and chronic pain associated with autoimmune joint inflammation. Suitable for long-term symptom control when used cautiously. > Ankylosing Spondylitis Improves spinal flexibility and reduces axial inflammation in spondyloarthropathies. Particularly effective in alleviating morning stiffness and inflammatory back pain. > Osteoarthritis Provides symptomatic relief in patients with degenerative joint disease, targeting pain and inflammation in weight-bearing joints such as the knees and hips. > Pediatric PDA (Off-label) Administered intravenously in preterm neonates to pharmacologically close a persistent ductus arteriosus, reducing the need for surgical intervention.
Indomethacin inhibits the COX enzymes, resulting in decreased synthesis of prostaglandins involved in inflammation, pain, and fever. It is considered one of the most potent NSAIDs, with rapid onset of action and robust anti-inflammatory efficacy. While effective, its risk of gastrointestinal and central nervous system side effects is higher compared to other NSAIDs, requiring careful dose selection and monitoring. It demonstrates favorable response in acute gout attacks, inflammatory joint conditions, and pain due to soft tissue inflammation.
Adults → Acute Gout: 50 mg orally or rectally three times daily until symptoms resolve → Bursitis/Tendonitis: - IR: 75–150 mg/day in 3–4 divided doses - Suppository: 50 mg up to 3 times daily - ER: 75 mg once or twice daily → Mild to Moderate Pain: 20 mg orally three times daily or 40 mg orally 2–3 times daily → Rheumatoid Arthritis, Ankylosing Spondylitis, Osteoarthritis: - IR: 25 mg 2–3 times daily; max 200 mg/day - Suppository: 50 mg once daily; max 200 mg/day - ER: 75 mg once or twice daily; may increase by 25–50 mg/day - Doses >200 mg/day not recommended Pediatrics → PDA (IV): - <48 hrs: 0.2 mg/kg IV, then 0.1 mg/kg IV ×2 - 2–7 days: 0.2 mg/kg IV ×3 - >7 days: 0.2 mg/kg, then 0.25 mg/kg IV ×2 → Juvenile Rheumatoid Arthritis (2–14 yrs): 1–2 mg/kg/day orally in divided doses (max 3 mg/kg/day or 150–200 mg/day) → Over 14 yrs: Use adult dosing for arthritis, spondylitis, bursitis, or tendonitis → Take with food or milk to reduce gastric irritation → If dose is missed, take as soon as remembered unless near the next dose—do not double dose → Avoid alcohol, prolonged use, or combining with other NSAIDs unless directed by a physician Renal/Hepatic Impairment: → Use with caution in renal or hepatic dysfunction → Monitor renal function in long-term therapy
Store below 25°C in a cool, dry place away from moisture and heat. Keep capsules in original blister packaging. Keep out of reach of children.
Common: abdominal pain, heartburn, nausea, dizziness, headache Less common: fluid retention, elevated blood pressure, rash Serious: gastrointestinal bleeding, peptic ulcers, CNS effects (confusion, depression, seizures) Stop use and seek medical attention if you experience black stools, vomiting blood, or severe stomach pain.
Pain eased quickly, convenient packaging
Pain eased quickly, easy to swallow
Capsules worked effectively, easy to include in routine
Felt relief shortly after taking, easy to swallow
Felt better shortly after taking, easy to carry
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