Exchange & Returns Information
Review Details
(0)
| Generic For | TEGRETOL |
|---|---|
| Active Ingredient | CARBAMAZEPINE |
| Strength | 100MG |
| Manufacturer | ABBOTT |
| Pack Size | Price Per Unit | Unit Price | QTY | CART | Best Coupon Price MAX DISCOUNT |
|---|---|---|---|---|---|
| 1 BOX - 200 TABLETS | $ 0.15 | $ 29.90 |
$ 25.42
Apply ZARVY26 (-15%)
You save $ 4.49
|
||
| 2 BOXES - 400 TABLETS | $ 0.16 | $ 64.90 |
$ 55.17
Apply ZARVY26 (-15%)
You save $ 9.74
|
||
| ★ Best Value 3 BOXES - 600 TABLETS | $ 0.16 | $ 97.90 |
$ 83.22
Apply ZARVY26 (-15%)
You save $ 14.69
|
Reference information will be available soon.
Mazetol 100 is a generic formulation of carbamazepine 100mg, widely used for managing a range of neurological and psychiatric disorders. As a tricyclic anticonvulsant and mood stabilizer, it targets excessive neuronal firing in the brain, providing therapeutic benefit in conditions such as epilepsy, bipolar disorder, and neuropathic pain. Its versatile action makes it valuable for both first-line and adjunctive treatment, especially in patients who do not respond well to lithium or experience intolerable side effects.
Epilepsy
Mazetol 100 is commonly prescribed to treat both partial and generalized tonic-clonic seizures. It works by stabilizing hyperexcited neural pathways and reducing the repetitive firing of brain neurons, which helps lower seizure frequency and severity.
Bipolar Disorder
This medication is also used as a mood stabilizer in patients with bipolar disorder, especially for controlling manic or hypomanic episodes. It serves as a suitable alternative in individuals who are intolerant or non-responsive to lithium therapy.
Depression, Anxiety, PTSD
Though not a first-line psychiatric treatment, Mazetol can offer emotional stabilization in select patients with mood instability, particularly in those with bipolar-related depressive symptoms or anxiety associated with PTSD.
Neuropathic Pain
Mazetol is frequently utilized to relieve chronic neuropathic pain, including trigeminal neuralgia and diabetic neuropathy. It acts by dampening abnormal pain signal transmission through overactive nerve pathways, leading to significant pain relief.
Carbamazepine works by blocking voltage-gated sodium channels in hyperexcited neurons, thereby stabilizing overactive nerve signals. In epilepsy, it reduces seizure frequency and severity by limiting abnormal neuronal firing. In bipolar disorder, it helps prevent mood swings by regulating neuronal activity in key emotional centers. Its analgesic effect in neuropathic pain results from disrupting pain signal transmission along damaged nerve pathways. It has also shown potential benefits in managing anxiety, PTSD, and bipolar-related depression, particularly in patients experiencing mood instability.
Adult Dosing Summary
Epilepsy – IR Form: Start with 200 mg twice daily or 100 mg QID (oral suspension). Titrate weekly by 200 mg/day in divided doses (TID or QID). Maintenance: 800–1200 mg/day. Maximum: 1600 mg/day.
ER Form: Use the same total daily dose as IR, divided BID; titrate similarly.
Trigeminal Neuralgia – Start at 100 mg BID or 50 mg QID (oral suspension). Increase by 200 mg/day until pain relief is achieved. Maintenance: 400–800 mg/day. Maximum: 1200 mg/day. Reassess every 3 months for potential taper.
Bipolar Disorder (ER Capsules) – Start at 200 mg BID. Titrate by 200 mg/day to achieve mood stabilization. Maximum: 1600 mg/day.
Pediatric Dosing Summary
<6 Years – 10–20 mg/kg/day divided BID–QID. Titrate weekly as tolerated. Maximum: 35 mg/kg/day.
6–12 Years – Start at 100 mg BID or 100 mg QID (oral suspension). Titrate weekly up to 100 mg/day. Maintenance: 400–800 mg/day. Maximum: 1000 mg/day.
>12 Years – Start at 200 mg BID or 100 mg QID (oral suspension). Titrate weekly by 200 mg/day. Maintenance: 800–1200 mg/day. Maximum: 1000 mg/day (12–15 yrs), 1200 mg/day (>15 yrs).
Additional Considerations
IR to ER conversion: Use the same total daily dose, divided BID.
Suspension use: Same total dose, but increase dosing frequency (TID–QID).
Polytherapy: Add gradually and adjust co-medications (e.g., phenytoin may need upward dose adjustment).
Monitoring: Regular plasma level checks ensure optimal therapeutic effect and minimize side effects.
Not suitable for absence seizures; may worsen generalized seizure types.
Store at room temperature below 25°C in a dry place, protected from direct light and humidity. Keep in original packaging and out of children's reach.
Common side effects include dizziness, drowsiness, nausea, blurred vision, and unsteadiness. Serious reactions may involve skin rashes (including Stevens-Johnson Syndrome), liver enzyme elevation, blood dyscrasias, and hyponatremia. Regular blood tests are recommended during long-term use to monitor liver function, electrolytes, and blood counts.
No reviews yet. Be the first to review this product!
No combo deals available at the moment.
