Exchange & Returns Information
Review Details
(0)
| Generic For | KOMBIGLYZE |
|---|---|
| Active Ingredient | SAXAGLIPTIN|METFORMIN |
| Strength | 5MG|1000MG |
| Manufacturer | DR REDDYS LABORATORIES |
| Pack Size | Price Per Unit | Unit Price | QTY | CART | Best Coupon Price MAX DISCOUNT |
|---|---|---|---|---|---|
| 1 BOX - 28 TABLETS | $ 1.77 | $ 49.60 |
$ 42.16
Apply ZARVY26 (-15%)
You save $ 7.44
|
||
| 2 BOXES - 56 TABLETS | $ 1.60 |
10% $ 99.20
$ 89.60
|
$ 76.16
Apply ZARVY26 (-15%)
You save $ 13.44
|
||
| ★ Best Value 3 BOXES - 84 TABLETS | $ 1.43 |
19% $ 148.80
$ 120.00
|
$ 102.00
Apply ZARVY26 (-15%)
You save $ 18.00
|
Reference information will be available soon.
Riax-M XR (Saxagliptin 5mg + Metformin 1000mg) is a combination therapy used for type 2 diabetes management. It effectively lowers blood sugar levels by combining two powerful agents: Saxagliptin (DPP-4 Inhibitor): Enhances insulin secretion and reduces glucagon levels, improving post-meal glucose control. Metformin (Biguanide): Reduces glucose production in the liver and increases insulin sensitivity for better blood sugar regulation. - Not for use in type 1 diabetes or diabetic ketoacidosis (DKA).
- First-Line Diabetes Treatment: Contains Metformin, making it an essential first-line therapy for managing Type 2 diabetes by lowering glucose production and improving insulin sensitivity. - DPP-4 Inhibition & Incretin Effect Enhancement: Saxagliptin (DPP-4 inhibitor) boosts GLP-1 hormone activity, enhancing insulin secretion after meals and reducing glucagon production, leading to better blood sugar control. - Blood Sugar Stabilization & HbA1c Reduction: Helps maintain consistent glucose levels throughout the day and supports long-term diabetes control by reducing HbA1c. - Weight Management Support: Aids in glycemic control, which can contribute to stabilizing or reducing weight in diabetic patients. - Cardiovascular Benefits: DPP-4 inhibitors have potential cardiovascular protective effects, potentially reducing heart disease risk in individuals with diabetes. - Not suitable for Type 1 diabetes or diabetic ketoacidosis (DKA).
Saxagliptin (DPP-4 Inhibitor): Blocks DPP-4 enzyme, allowing incretin hormones (GLP-1, GIP) to stay active longer. Increases insulin release and reduces glucagon levels, lowering post-meal glucose spikes. Metformin (Biguanide): Decreases glucose production in the liver. Improves insulin sensitivity, helping cells use glucose efficiently. Delays intestinal glucose absorption, contributing to better glucose control. - This combination ensures stable blood sugar levels throughout the day.
For Diabetes > First-Line Therapies: Metformin - Take Riax-M XR as prescribed for the management of type 2 diabetes. - Standard dose: Once daily with the evening meal to optimize blood sugar control. - Metformin component: Helps reduce glucose production in the liver and improves insulin sensitivity. - Saxagliptin component: A DPP-4 inhibitor that enhances insulin secretion and reduces glucose spikes. - Maximum dose: Metformin 2000mg/day, Saxagliptin 5mg/day. For Diabetes > DPP-4 Inhibitors - Enhances natural insulin secretion by inhibiting the breakdown of incretin hormones. - Helps control blood sugar levels throughout the day without increasing the risk of hypoglycemia. - Ideal for combination therapy with other antidiabetic drugs, including SGLT-2 inhibitors or insulin. For Diet > Glycemic Control - Helps stabilize post-meal blood sugar levels, reducing sudden glucose spikes. - Supports better carbohydrate metabolism, making it beneficial for individuals on a low-GI or diabetic-friendly diet. - Can be integrated with diet and exercise for optimal weight and metabolic control. For Lifestyle-Related Diseases > Cardiovascular Diseases - Metformin and Saxagliptin have been shown to provide cardiovascular benefits in diabetic patients. - May help reduce the risk of heart disease by controlling blood pressure, cholesterol, and blood glucose levels. - Helps maintain vascular health, reducing the likelihood of diabetes-related complications. Administration - Take once daily with food, preferably in the evening. - Swallow whole with a full glass of water; do not crush or chew. - If a dose is missed, do not double the next dose—take it at the next scheduled time. - Regular kidney function monitoring is advised, especially for patients with renal impairment. - Consult a doctor for dose adjustments based on glycemic response and kidney function.
- Store in a cool, dry place, away from moisture and direct sunlight. - Keep in original packaging to maintain tablet stability. - Do not refrigerate or freeze. - Keep out of reach of children to avoid accidental ingestion. - Always check the expiration date before use.
- Common Side Effects Mild nausea, diarrhea, or stomach discomfort. Headache or dizziness. Hypoglycemia (when combined with insulin or sulfonylureas). - Less Common Side Effects Fatigue or weakness. Mild swelling in hands or feet. Increased risk of urinary tract infections (UTIs). - Serious Side Effects (Seek Medical Attention if These Occur) Lactic Acidosis – Unexplained muscle pain, breathing difficulties, or extreme tiredness. Severe Hypoglycemia – Confusion, shaking, sweating, or fainting. Pancreatitis – Severe abdominal pain, nausea, vomiting. - Regular kidney function tests are recommended when using metformin-based treatments.
No reviews yet. Be the first to review this product!
No combo deals available at the moment.
