Oxramet S XR 1000, Metformin + Saxagliptin, Diabetes Care, Online Pharmacy, ZarvyPharm
DIABETES BEAUTY Liver Health Cardiovascular Diseases Dapagliflozin Metformin +11

Oxramet S XR 500

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Generic For N/A
Active Ingredient DAPAGLIFLOZIN|SITAGLIPTIN|METFORMIN
Strength 10MG|100MG|500MG
Manufacturer SUN PHARMA
Oxramet S XR 1000 28 tablets front box packaging
Oxramet S XR 1000 blister strip with tablets
Oxramet S XR 1000 28 tablets back side packaging
Oxramet S XR 1000 28 tablets front box packaging
Oxramet S XR 1000 blister strip with tablets
Oxramet S XR 1000 28 tablets back side packaging
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Product Description

Oxramet S XR 500 is a combination therapy for Type 2 Diabetes, containing Dapagliflozin (SGLT-2 Inhibitor) 10mg, Sitagliptin (DPP-4 Inhibitor) 100mg, and Metformin (First-Line Therapy) 500mg. This triple-action formula effectively lowers blood sugar levels by enhancing insulin sensitivity, reducing hepatic glucose production, and increasing glucose excretion through urine. As part of a comprehensive diabetes management strategy, Oxramet S XR 500 improves Glycemic Control, helps prevent Cardiovascular Diseases, and supports Liver Health by regulating hepatic glucose metabolism. This extended-release (XR) formulation ensures gradual absorption, reducing gastrointestinal side effects commonly associated with Metformin.

Indications & Uses

- Blood Sugar Regulation: This triple-therapy controls blood sugar through SGLT-2 inhibition, DPP-4 inhibition, and Metformin action. - First-Line Diabetes Treatment: Metformin enhances insulin sensitivity and suppresses excess glucose production in the liver. - SGLT-2 Inhibitor Action: Dapagliflozin increases glucose excretion through urine, helping reduce blood sugar levels and support weight management. - DPP-4 Inhibitor Action: Sitagliptin improves insulin secretion and prevents excessive glucose release after meals. - Cardiovascular Protection: Helps prevent Cardiovascular Diseases by maintaining stable blood sugar levels and lowering vascular stress. - Liver Health Support: Reduces hepatic glucose output, supporting liver function and improving metabolic stability.

Benefits & Effectiveness

Oxramet S XR 500 works through a three-mechanism approach: - Dapagliflozin (SGLT-2 Inhibitor): Prevents glucose reabsorption in the kidneys, promoting glucose excretion and improving blood sugar control. - Sitagliptin (DPP-4 Inhibitor): Enhances insulin release and suppresses post-meal glucose spikes. - Metformin (First-Line Therapy): Reduces hepatic glucose production, increases insulin sensitivity, and improves Glycemic Control. These mechanisms work together to maintain metabolic balance, reduce the risk of Cardiovascular Diseases, and support Liver Health.

Directions for Use

For Diabetes > First Line Therapies: Metformin - Take Oxramet S XR 500 as prescribed for type 2 diabetes management. - Standard dosage: One tablet once or twice daily, preferably with meals to reduce stomach discomfort. - Metformin helps lower liver glucose production and improves insulin sensitivity. - Extended-release (XR) formulation ensures gradual drug release, reducing side effects like nausea. - Regular blood sugar monitoring is necessary for effective glycemic control. For Diabetes > SGLT-2 Inhibitors - Dapagliflozin removes excess glucose through urination, helping lower blood sugar levels. - Promotes weight loss and reduces blood pressure, offering additional metabolic benefits. - Increased urination is common—stay hydrated to prevent dehydration. - Not recommended for patients with severe kidney impairment (eGFR <30 mL/min/1.73m²). For Diabetes > DPP-4 Inhibitors - Sitagliptin helps enhance insulin secretion and reduce excess glucose production. - Supports post-meal blood sugar regulation and prevents sudden glucose spikes. - Can be combined with other antidiabetic medications for enhanced glycemic control. - Suitable for patients who require additional support beyond Metformin and SGLT-2 inhibitors. For Diet > Glycemic Control - Helps stabilize blood sugar levels, reducing post-meal glucose fluctuations. - Works best when combined with a balanced diet and regular exercise. - Reduces insulin resistance, promoting long-term diabetes control. For Lifestyle-Related Diseases > Cardiovascular Diseases - Dapagliflozin is known to lower cardiovascular risks in diabetic patients with heart disease. - Reduces the risk of heart failure by improving fluid balance and vascular health. - Helps lower blood pressure, benefiting individuals with hypertension. For Stomach & Liver & Digestive System > Liver Health - Metformin is beneficial for liver health, helping reduce fatty liver in diabetic patients. - Improves liver enzyme levels in individuals with non-alcoholic fatty liver disease (NAFLD). - Supports better metabolic function by regulating glucose and lipid metabolism. Administration - Take once or twice daily with meals to reduce stomach discomfort. - Swallow whole—do not crush or chew, as it is an extended-release (XR) formulation. - Increase water intake, as SGLT-2 inhibitors may increase urination. - Do not double the dose if one is missed. - Consult a doctor if you experience signs of dehydration, dizziness, or recurrent urinary tract infections.

Storage

- Store in a cool, dry place, away from heat and moisture. - Keep in original packaging for stability. - Ensure it is out of reach of children and pets.

Possible Side Effects

While Oxramet S XR 500 is well tolerated, some users may experience: - Increased urination and thirst (due to Dapagliflozin). - Mild dehydration, dizziness, or electrolyte imbalance. - Gastrointestinal discomfort, nausea, or diarrhea (Metformin-related). - Urinary tract infections (UTIs) and genital yeast infections. - Hypoglycemia when combined with other antidiabetic medications. Severe side effects, such as lactic acidosis or ketoacidosis, require immediate medical attention.

FAQs

Oxramet S XR 500 is a combination therapy for Type 2 diabetes, containing Dapagliflozin (SGLT-2 inhibitor), Sitagliptin (DPP-4 inhibitor), and Metformin (First-Line Therapy). It enhances insulin sensitivity, regulates blood sugar, and supports weight management.
It works through three key mechanisms: - Dapagliflozin increases glucose excretion, lowering blood sugar levels. - Sitagliptin enhances insulin secretion and prevents excessive glucose release after meals. - Metformin reduces glucose production in the liver and improves insulin efficiency. Together, these mechanisms provide metabolic stability and support cardiovascular and liver health.
Yes, stable blood sugar levels reduce the risk of Cardiovascular Diseases, lowering vascular stress and preventing complications.
Yes, Metformin reduces hepatic glucose production, promoting Liver Health and metabolic balance.
Take one tablet once or twice daily with food. Swallow whole—do not crush or chew. Stay hydrated, as increased urination is common.
Common side effects include increased urination, mild dehydration, dizziness, nausea, diarrhea, and UTIs. These effects are generally mild and temporary.
Not recommended for individuals with severe kidney disease, Type 1 diabetes, or a history of lactic acidosis. Pregnant or breastfeeding women should consult their doctor.

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