Xigduo XR 10/500mg, Dapagliflozin + Metformin, Extended-Release Diabetes Therapy, SGLT2 + Metformin Combination, Heart & Kidney Protection, Online Pharmacy
DIABETES BEAUTY Liver Health Cardiovascular Diseases Metformin DIET +10

Xigduo XR 10/500mg

★★★★★
★★★★★
4.9

(9)

Drug Type Original
Active Ingredient DAPAGLIFLOZIN|METFORMIN
Strength 10MG|500MG
Manufacturer ASTRAZENECA
Xigduo XR 10/500mg tablets box (Dapagliflozin 10mg + Metformin 500mg ER) front packaging view
Xigduo XR 10/500mg tablets back side of white carton with dosage and prescribing information
Xigduo XR 10/500mg silver blister strip with oval white film-coated tablets
Xigduo XR 10/500mg tablets box (Dapagliflozin 10mg + Metformin 500mg ER) front packaging view
Xigduo XR 10/500mg tablets back side of white carton with dosage and prescribing information
Xigduo XR 10/500mg silver blister strip with oval white film-coated tablets
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Product Description

Xigduo XR 10/500mg is an original branded medication developed by AstraZeneca for Type 2 diabetes management. It combines Dapagliflozin 10mg (an SGLT-2 inhibitor) and Metformin 500mg (a first-line diabetes treatment) in an extended-release (XR) formulation. This combination effectively controls blood sugar levels, supports weight management, and may offer cardiovascular and liver health benefits. The extended-release design allows for gradual absorption, reducing the risk of gastrointestinal discomfort associated with immediate-release Metformin.

Indications & Uses

- First-Line Diabetes Treatment: Metformin enhances insulin sensitivity and reduces glucose production in the liver. - Blood Sugar Regulation: Dapagliflozin helps eliminate excess glucose by blocking reabsorption in the kidneys. - Weight Management Support: Promotes glycemic control, assisting in gradual weight reduction. - Cardiovascular Benefits: Dapagliflozin may help reduce the risk of heart failure and cardiovascular complications. - Liver Health Support: May have potential benefits in managing non-alcoholic fatty liver disease (NAFLD).

Benefits & Effectiveness

Xigduo XR 10/500mg utilizes a dual mechanism: - Metformin (First-Line Therapy) reduces glucose production in the liver and enhances insulin response. - Dapagliflozin (SGLT-2 Inhibitor) blocks glucose reabsorption in the kidneys, leading to increased glucose excretion and improved blood sugar control. - The extended-release formulation ensures gradual absorption of Metformin, minimizing gastrointestinal side effects.

Directions for Use

- Take one tablet (10mg/500mg) once daily, preferably with the first meal of the day. - Swallow the tablet whole—do not crush or chew, as it is an extended-release (XR) formulation. - Supports glycemic control, helping some patients with weight management. - Ensure proper hydration, as increased urination is a common effect due to SGLT-2 inhibition.

Storage

- Store in a cool, dry place, away from direct sunlight, heat, and moisture. - Keep the tablets in their original packaging to maintain potency. - Ensure the medication is out of reach of children and pets.

Possible Side Effects

While generally well-tolerated, some users may experience mild side effects such as: - Increased urination and thirst - Mild dehydration or dizziness - Gastrointestinal discomfort, nausea, or diarrhea (due to Metformin) - Urinary tract infections (UTIs) and genital yeast infections (due to SGLT-2 inhibition) - Low blood sugar when taken with other diabetes medications Important: Pregnant women should consult their doctor before handling or using this medication. If severe side effects occur, such as lactic acidosis or ketoacidosis, seek medical attention immediately.

FAQs

Xigduo XR 10/500mg is an original branded medication for Type 2 diabetes management, developed by AstraZeneca. It contains Dapagliflozin, an SGLT-2 inhibitor that promotes glucose excretion through urine, and Metformin, a first-line diabetes treatment that improves insulin sensitivity. This combination helps control blood sugar levels, supports weight management, and may offer cardiovascular and liver health benefits.
Xigduo XR 10/500mg works through a dual mechanism: Dapagliflozin blocks SGLT-2 in the kidneys, preventing glucose reabsorption and increasing glucose excretion, thereby lowering blood sugar levels. Metformin reduces glucose production in the liver and enhances insulin sensitivity, improving blood sugar control. The extended-release (XR) formulation ensures gradual absorption of Metformin, reducing gastrointestinal side effects.
Common side effects may include increased urination, mild dehydration, dizziness, gastrointestinal discomfort (nausea, diarrhea), urinary tract infections (UTIs), and genital yeast infections. These effects are usually mild and temporary.
Take one tablet (10mg/500mg) once daily, preferably with your first meal of the day. Swallow the tablet whole—do not crush or chew, as it is an extended-release (XR) formulation. Stay hydrated, as increased urination is a common effect of this medication.
Store Xigduo XR 10/500mg in a cool, dry place, away from direct sunlight and moisture. Keep it in its original packaging and ensure it’s out of reach of children and pets.
This medication is not recommended for individuals with severe kidney disease, Type 1 diabetes, or a history of lactic acidosis. Pregnant or breastfeeding women should consult their doctor before use.

Ratings & Reviews

Reviewed by 9 Users

4.9/5
★★★★★
★★★★★
5★
89%
4★
11%
3★
0%
2★
0%
1★
0%

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Product
N**h G**n Feb 07, 2024
★★★★★
★★★★★

Everything arrived intact

No damage or tampering. Sealed and fresh. 📦

Product
A**a R**n Jul 22, 2023
★★★★★
★★★★★

การสั่งซื้อราบรื่นและจัดส่งไวมาก

ฉันสั่งผ่านมือถือ ขั้นตอนง่ายและของมาถึงใน 6 วัน ห่อแน่นหนา มีข้อมูลชัดเจน เหมาะกับคนที่สั่งจากต่างประเทศจริง ๆ

Product
J**a N**n May 14, 2023
★★★★★
★★★★★

Insurance option is a best relief evevr

Chose standard insurance and it gave me peace of mind.

Product
E**n B**s Mar 20, 2023
★★★★★
★★★★★

Loyal customer thanks to clean system

Been ordering here for over a year. UI, shipping, and updates are consistently great. Makes long-term use hassle-free.

Product
N**n C**w Jan 25, 2023
★★★★★
★★★★★

Good info made it easy to decide

Description gave just enough clarity to pick the right one.

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