Exchange & Returns Information
Review Details
(8)
| Drug Type | Original |
|---|---|
| Active Ingredient | GOSERELIN |
| Strength | 10.8MG |
| Manufacturer | ASTRA ZENECA |
| Pack Size | Price Per Unit | Unit Price | QTY | CART | Best Coupon Price MAX DISCOUNT |
|---|---|---|---|---|---|
| 1 BOX - 1 VIAL | $ 667.00 | $ 667.00 |
$ 566.95
Apply ZARVY26 (-15%)
You save $ 100.05
|
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| 2 BOXES - 2 VIALS | $ 671.00 | $ 1,342.00 |
$ 1,140.70
Apply ZARVY26 (-15%)
You save $ 201.30
|
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| ★ Best Value 3 BOXES - 3 VIALS | $ 672.33 | $ 2,017.00 |
$ 1,714.45
Apply ZARVY26 (-15%)
You save $ 302.55
|
Reference information will be available soon.
Zoladex LA 10.8 is a long-acting subcutaneous depot injection containing 10.8mg of goserelin, a potent synthetic gonadotropin-releasing hormone (GnRH) agonist. Designed to provide sustained hormonal suppression over a 12-week period, it acts by desensitizing pituitary GnRH receptors, thereby reducing luteinizing hormone (LH) and follicle-stimulating hormone (FSH) levels. This leads to a significant drop in circulating testosterone in men and estrogen in women, inducing a reversible state of chemical castration. Zoladex LA 10.8 is a foundational therapy in the palliative management of advanced or metastatic prostate cancer, and is also used in hormone receptor-positive breast cancer in premenopausal women. Its extended duration allows for reduced injection frequency while maintaining consistent hormone suppression, making it ideal for long-term treatment strategies.
- AntiCancer Drugs > Prostate Cancer Used for the management of advanced or locally confined prostate cancer. Zoladex LA 10.8 suppresses testicular testosterone production, thereby inhibiting androgen-driven tumor growth. It serves as a non-surgical alternative to orchiectomy and supports improved patient adherence through quarterly dosing. > HR+ Breast Cancer in Premenopausal Women Utilized to induce ovarian suppression in hormone receptor-positive breast cancer patients who are not postmenopausal. Frequently combined with aromatase inhibitors, it helps reduce estrogen-driven tumor progression. - Hormones & Menopausal Symptoms - FEMTECH > Endometriosis Provides temporary suppression of estrogen to relieve pelvic pain, reduce menstrual bleeding, and minimize ectopic endometrial tissue growth. Offers a reversible hypoestrogenic hormonal environment. > Uterine Fibroid Used preoperatively to shrink fibroid volume and improve surgical outcomes. Zoladex helps reduce menorrhagia and anemia by limiting estrogen-mediated fibroid growth. > Ovulation Suppression in IVF Employed in assisted reproduction protocols to prevent premature LH surge and synchronize follicular development. Enhances control over the timing of ovulation in patients undergoing IVF.
Goserelin induces a biphasic hormonal response: an initial surge in LH and FSH followed by receptor downregulation and suppression of gonadotropin release. This results in a profound decrease in gonadal steroidogenesis. In prostate cancer, testosterone reduction to castrate levels reduces tumor burden and delays disease progression. In hormone-sensitive breast cancer, estrogen suppression is vital for controlling tumor growth. Its effects are reversible upon discontinuation, making it a flexible alternative to surgical hormone suppression. The 10.8mg formulation ensures continuous pharmacologic activity for 12 weeks, enhancing treatment convenience and improving patient quality of life during chronic therapy.
Prostate Cancer (Advanced, Palliative): → 10.8 mg subcutaneously every 12 weeks → Alternatively, 3.6 mg every 28 days → Therapy is long-term unless clinically contraindicated → Used to achieve and maintain castrate-level testosterone Prostate Cancer (Locally Confined, Neoadjuvant + Radiotherapy): → Option 1: 3.6 mg once, then 10.8 mg after 28 days → Option 2: 3.6 mg every 28 days for 4 doses (2 before, 2 during radiation) → Supports tumor reduction and radiosensitivity enhancement in T2b–T4 patients Endometriosis: → 3.6 mg subcutaneously every 28 days → Recommended duration: 6 months maximum → Reduces estrogen stimulation of ectopic endometrial tissue Breast Cancer (Palliative, Premenopausal Women): → 3.6 mg subcutaneously every 28 days → Used with aromatase inhibitors for complete estrogen suppression → Suitable for long-term use unless otherwise contraindicated Endometrial Thinning (Pre-Ablation): → 3.6 mg once OR twice (4 weeks apart) → Surgery scheduled 4 weeks after last injection → Helps reduce endometrial thickness and bleeding risk Administration Tips: → Administer subcutaneously into the lower abdomen using the preloaded syringe → Do not manipulate or withdraw implant after insertion → Rotate injection sites periodically → Supplement with calcium and vitamin D if treatment extends beyond 6 months
Store below 25°C in original packaging to protect from moisture and light. Do not freeze. Use immediately after opening the foil pouch. Keep out of reach of children. Dispose of used needles and syringes in accordance with local regulations.
Common: hot flashes, libido decrease, injection site pain, emotional lability, sweating Less Common: headache, skin changes, fatigue, gynecomastia (men), irregular bleeding (women) Rare: bone demineralization, cardiovascular risk, glucose intolerance, tumor flare in prostate cancer Seek medical evaluation if symptoms such as persistent bone pain, mood disturbance, or chest discomfort occur.
Getting my Zoladex injection on schedule is critical for my treatment. This pharmacy has been 100% reliable every single time.
我的前列腺癌治疗需要定期注射诺雷德（Zoladex）。这家网站能准时送达，服务可靠，让我非常放心。
My Zoladex injection is essential for my prostate cancer treatment. I'm grateful to have a pharmacy that provides such a consistent and reliable supply.
Managing my endometriosis is a long-term battle, and this pharmacy helps make it more manageable. Their website is so well-designed that reordering my Zoladex injection is one less thing to worry about. The user interface is simple, and I can set up my next shipment in advance. This seamless, stress-free process is a small comfort that makes a big difference.
For a medication this important, you need a source you can completely trust. This site has earned my confidence through months of flawless service.
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