Keytruda 100, Pembrolizumab, Immunotherapy, Cancer Treatment, ZarvyPharm
AntiCancer Drugs Ovarian Cancer Kidney Cancer Colorectal Cancer(CRC) Breast Cancer Cervical Cancer +1

Keytruda 100, Injection - 4ml

★★★★★
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5

(36)

Drug Type Original
Active Ingredient PEMBROLIZUMAB
Strength 100MG
Manufacturer MSD
Keytruda 100 Injection 4ml front box packaging
Keytruda 100 Injection 4ml vial close-up
Keytruda 100 Injection 4ml vial with outer carton
Keytruda 100 Injection 4ml front box packaging
Keytruda 100 Injection 4ml vial close-up
Keytruda 100 Injection 4ml vial with outer carton
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Product Description

Keytruda 100 is a 100mg/4ml injectable formulation of pembrolizumab, a highly selective humanized monoclonal antibody that blocks the interaction between PD-1 and its ligands (PD-L1 and PD-L2). This blockade reinvigorates exhausted T-cells and restores antitumor immunity, making it a cornerstone of immune checkpoint inhibitor therapy. Pembrolizumab is used across a wide range of solid tumors and hematologic malignancies, either as monotherapy or in combination with chemotherapy, targeted agents, or other immunotherapies. It is administered via intravenous infusion and is dosed either every 3 or 6 weeks depending on the treatment protocol.

Indications & Uses

- AntiCancer Drugs > Non-Small Cell Lung Cancer (NSCLC) Used as first-line monotherapy in PD-L1 expressing NSCLC (TPS ≥1%) or in combination with platinum-based chemotherapy. Effective in both squamous and non-squamous subtypes. > Melanoma Approved for unresectable or metastatic melanoma and as adjuvant therapy following resection of stage III disease. Long-term responses have been observed. > Head and Neck Squamous Cell Carcinoma (HNSCC) Used in recurrent or metastatic HNSCC either as monotherapy or combined with platinum + 5-FU. PD-L1 CPS ≥1% is a key biomarker. > Urothelial Carcinoma (Bladder Cancer) Indicated for platinum-refractory metastatic disease or in combination with enfortumab vedotin. Also used for BCG-unresponsive NMIBC (non-muscle invasive bladder cancer). > Triple-Negative Breast Cancer (TNBC) Used in PD-L1 positive TNBC in combination with chemotherapy (e.g., paclitaxel) for advanced or early-stage neoadjuvant/adjuvant treatment. > Cervical Cancer Administered with chemotherapy ± bevacizumab for PD-L1 positive recurrent or metastatic disease. Also used in chemoradiotherapy regimens for locally advanced cases. > Endometrial Cancer Used as monotherapy in MSI-H/dMMR tumors or in combination with lenvatinib for pMMR or MSS tumors. > Gastric, Esophageal, Liver, Biliary Cancers Approved for various indications depending on PD-L1 expression, MSI/TMB status, or in combination strategies with platinum-based agents or atezolizumab.

Benefits & Effectiveness

- Blocks PD-1 receptor, restoring T-cell activity and immune surveillance - Promotes sustained antitumor responses in various advanced malignancies - Shows durable clinical benefit in both monotherapy and combination regimens - Biomarker-based efficacy: PD-L1, MSI-H, dMMR, TMB-H

Directions for Use

1. Adult dose: → 200 mg IV every 3 weeks or 400 mg IV every 6 weeks → Administer over 30 minutes → Continue until disease progression, unacceptable toxicity, or up to 12–24 months depending on indication 2. Indications: → NSCLC (mono or combo) → Melanoma (unresectable, metastatic, or adjuvant) → HNSCC, TNBC, Cervical, Endometrial, Gastric, Esophageal, RCC, HCC, cSCC → Lymphomas: cHL, PMBCL → Rare tumors: Merkel cell carcinoma, biliary cancer → Biomarker-based use: MSI-H, TMB-H, PD-L1, dMMR tumors 3. Pediatric dose (≥12 years): → 2 mg/kg IV every 3 weeks (max 200 mg) → Duration: up to 24 months 4. Admin notes: → Administer first when given with other drugs → Monitor for immune-related adverse events (colitis, thyroiditis, pneumonitis, etc.)

Storage

Store at 2–8°C. Do not freeze or shake. Keep in original carton to protect from light. Use immediately after dilution; discard any unused portion.

Possible Side Effects

Common: fatigue, nausea, rash, pruritus, diarrhea, arthralgia Immune-related AEs: pneumonitis, colitis, hepatitis, nephritis, endocrinopathies (thyroiditis, hypophysitis, adrenal insufficiency) Severe: infusion reactions, myocarditis, encephalitis Monitoring: LFTs, TSH/Free T4, renal function, glucose, cortisol, signs of immune AEs

FAQs

Keytruda is an immune checkpoint inhibitor used to treat various cancers like lung cancer, melanoma, head and neck cancer, bladder cancer, and more.
It enhances the body’s immune response rather than directly killing cancer cells like traditional chemotherapy.
No, its use depends on cancer type, biomarker status (PD-L1, MSI-H, etc.), and approval status for specific tumors.
Treatment typically continues until disease progression or unacceptable toxicity, usually up to 2 years.
Patients should be screened for autoimmune diseases, active infections (HBV, HCV, TB), and thyroid/adrenal disorders before starting treatment.

Ratings & Reviews

Reviewed by 36 Users

5/5
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5★
100%
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Product
J**s A**n Mar 10, 2023
★★★★★
★★★★★

Neatly sealed vial

The product was well packed with no damage or leakage.

Product
I**a H**s Mar 10, 2023
★★★★★
★★★★★

Appreciated flexible payment methods

Having multiple options made the checkout convenient.

Product
I**a H**s Mar 10, 2023
★★★★★
★★★★★

Worked fine

The injection arrived without any problem.

Product
J**s W**n Mar 09, 2023
★★★★★
★★★★★

Helpful support and clear communication

I had a question about tracking, and the team updated me promptly. The order arrived intact soon after, exactly as expected.

Product
J**s W**n Mar 08, 2023
★★★★★
★★★★★

Professional handling of my inquiry

I had a small concern about payment confirmation, but the support team answered within an hour. Delivery followed promptly, and everything arrived in excellent condition.

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