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Review Details
(32)
| Generic For | PROGYNOVA |
|---|---|
| Active Ingredient | ESTRADIOL VALERATE |
| Strength | 2MG |
| Manufacturer | ZYDUS CADILA |
| Pack Size | Price Per Unit | Unit Price | QTY | CART | Best Coupon Price MAX DISCOUNT |
|---|---|---|---|---|---|
| 1 BOX - 28 TABLETS | $ 0.75 | $ 20.90 |
$ 17.77
Apply ZARVY26 (-15%)
You save $ 3.14
|
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| 2 BOXES - 56 TABLETS | $ 0.87 | $ 48.90 |
$ 41.57
Apply ZARVY26 (-15%)
You save $ 7.34
|
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| ★ Best Value 3 BOXES - 84 TABLETS | $ 0.92 | $ 76.90 |
$ 65.37
Apply ZARVY26 (-15%)
You save $ 11.54
|
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Progynova 2mg Tablet is a high-strength oral estrogen formulation containing Estradiol Valerate, a synthetic ester of estradiol. Designed for systemic hormone replacement, it addresses multiple estrogen-deficient conditions across gynecology and oncology. Its extended bioavailability and stable hormone delivery make it suitable for long-term use in managing vasomotor symptoms, atrophic changes, and osteoporosis prevention. The 2mg dosage offers increased therapeutic efficacy for women with moderate to severe symptoms or those requiring aggressive hormonal support due to surgical menopause, ovarian insufficiency, or cancer-related needs.
- HORMONES & MENOPAUSAL SYMPTOMS > Menopausal Hormone Therapy Effectively relieves hot flashes, night sweats, sleep disturbances, and mood swings in postmenopausal women. - FEMTECH > Menstrual Control Used in cycle regulation and hormonal stabilization, particularly after hysterectomy or oophorectomy. - FEMTECH > Vaginal & Urethral Atrophy Improves vaginal lubrication and elasticity, reducing discomfort and dyspareunia in estrogen-deficient patients. - LIFESTYLE-RELATED DISEASES > Osteoporosis Maintains bone mineral density and reduces fracture risk, especially in women not tolerating non-hormonal agents. - DISEASES/SYMPTOMS > Hypoestrogenism Prescribed for estrogen replacement in women with ovarian failure, premature menopause, or congenital deficiency. - AntiCancer Drugs > Prostate Cancer Used as antiandrogen therapy by suppressing testosterone in androgen-sensitive tumors. - AntiCancer Drugs > Breast Cancer Occasionally indicated in hormone-sensitive metastatic breast cancer in elderly or palliative settings. - AntiCancer Drugs > Others (for off-label hormonal modulation) Applied in transgender HRT and in certain off-label protocols for hormone balancing.
Estradiol Valerate is hydrolyzed into estradiol after oral ingestion, offering stable estrogenic effects through receptor-mediated transcriptional activation. It promotes endometrial proliferation, inhibits gonadotropin secretion, and enhances collagen synthesis in connective tissues. Systemic benefits include cardiovascular support, bone density preservation, and neuroendocrine balance. In higher doses, it serves as an antiandrogen by disrupting testosterone-driven tumor growth.
1. Postmenopausal Symptoms (e.g., vasomotor) - Oral: 1–2 mg daily in a cyclic schedule (3 weeks on, 1 week off) - Transdermal Patch: - Twice-weekly: Start with 0.0375–0.05 mg/day; maintain 0.025–0.1 mg/day - Once-weekly: Start with 0.025 mg/day; adjust up to 0.1 mg/day - Gel (Divigel): 0.25–1.25 mg/day to inner thigh - Metered Pump (Estrogel): 0.52–0.75 mg/day to arm - Spray (Evamist): 1.53 mg/spray, apply 1–3 times/day - Vaginal Ring (Femring): Insert every 90 days - IM Injection: - Cypionate: 1–5 mg every 3–4 weeks - Valerate: 10–20 mg every 4 weeks 2. Atrophic Urethritis / Vaginitis - Same dosing as for menopausal symptoms - Prefer localized vaginal forms for site-specific relief 3. Hypoestrogenism / Ovarian Failure - Oral: 1–2 mg/day continuously - Patch or IM as adjunct or alternative based on tolerance 4. Osteoporosis Prevention - Oral: ≥0.5 mg/day - Patch options: - Twice-weekly: 0.025 mg/day - Once-weekly (Climara): 0.025 mg/day - Ultra-low dose (Menostar): 0.014 mg/day - Evaluate fracture risk before initiating hormone therapy 5. Breast Cancer (Palliative Use) - Oral: 10 mg three times daily for ≥3 months 6. Prostate Cancer (Palliative Use) - Oral: 1–2 mg three times daily - IM: Estradiol valerate ≥30 mg every 1–2 weeks General Notes: - Always begin with the lowest effective dose and titrate as needed - Co-administer a progestogen in women with an intact uterus - Monitor endometrial health, lipid profile, and cardiovascular status - Reassess therapeutic need every 3 to 6 months
Store at a temperature below 25°C. Protect from moisture, heat, and direct light. Keep in original blister packaging until use. Keep out of reach of children.
Common adverse effects include breast tenderness, nausea, bloating, mood changes, and headache. Serious risks may include venous thromboembolism, gallbladder disease, and endometrial hyperplasia. Long-term use requires periodic monitoring of hormone-sensitive organs and cardiovascular markers.
Il prezzo del Progynova è molto più basso rispetto alla farmacia locale e la consegna è stata sorprendentemente rapida. Servizio eccellente.
I shopped around, and this site consistently offers the best price for Progynova 2mg. Highly recommend for value.
I accidentally ordered the wrong dosage and didn't realize until after I received the confirmation email. I immediately contacted their customer service, expecting a complicated process. Instead, the agent I spoke with was incredibly understanding and efficient. She canceled the incorrect order, helped me place the new one for the 2mg tablets, and ensured I was refunded the difference promptly. This hassle-free, human-centric support is why I will continue to use and recommend this pharmacy.
I like that I get notifications when my order is shipped and out for delivery. Keeps me informed.
I'm not very tech-savvy, but I find this website very easy to use on my own.
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