Estraheal 2mg, Estradiol Valerate, Women’s Health, Hormone Replacement Therapy, Online Pharmacy
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Estraheal 2mg Tablet

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Generic For PROGYNOVA
Active Ingredient ESTRADIOL VALERATE
Strength 2MG
Manufacturer HEALING PHARMA
Estraheal 2 28 tablets blister pack estradiol hormone replacement therapy online pharmacy
Estraheal 2 28 tablets box with blister strips estradiol estrogen medicine online pharmacy
Estraheal 2 28 tablets branded box packaging estradiol hormone therapy online pharmacy
Estraheal 2 28 tablets blister pack estradiol hormone replacement therapy online pharmacy
Estraheal 2 28 tablets box with blister strips estradiol estrogen medicine online pharmacy
Estraheal 2 28 tablets branded box packaging estradiol hormone therapy online pharmacy
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Product Description

Estraheal 2mg Tablet contains Estradiol Valerate, a long-acting estrogen ester used in hormone replacement therapy and selected oncologic settings. Its primary action is to replenish estrogen levels in individuals with deficient endogenous production, providing symptom relief and long-term protective benefits. With a pharmacokinetic profile optimized for consistent absorption and conversion to active estradiol, it supports both systemic and localized treatment goals across gynecologic, skeletal, urologic, and endocrine domains.

Indications & Uses

  • HORMONES & MENOPAUSAL SYMPTOMS > Menopausal Hormone Therapy Relieves vasomotor instability, night sweats, sleep disruptions, and other menopausal discomforts.
  • FEMTECH > Menstrual Control Used to regulate cycles in women with premature ovarian insufficiency, amenorrhea, or post-surgical menopause.
  • FEMTECH > Vaginal & Urethral Atrophy Alleviates genitourinary syndrome of menopause (GSM), including dryness, discomfort, and urinary irritation.
  • LIFESTYLE-RELATED DISEASES > Osteoporosis Helps preserve bone mineral density and reduces fracture risk in estrogen-deficient populations.
  • DISEASES/SYMPTOMS > Hypoestrogenism Treats low estrogen conditions such as post-oophorectomy states, hypogonadism, or functional hypothalamic amenorrhea.
  • AntiCancer Drugs > Prostate Cancer Applied in male patients to suppress androgen production in hormone-sensitive prostate cancer.
  • AntiCancer Drugs > Breast Cancer Administered as a secondary option in postmenopausal breast cancer where estrogen modulation is indicated.
  • AntiCancer Drugs > Others (for off-label hormonal modulation) Used in specialized endocrine regimens including transgender hormone therapy or rare syndromic estrogen deficiency.

Benefits & Effectiveness

Estradiol Valerate undergoes hepatic hydrolysis to release bioactive estradiol, which binds to estrogen receptors (ERα and ERβ) across various tissues. Its systemic effects include thermoregulatory stabilization, promotion of endometrial integrity, enhancement of vaginal epithelium, and reduction of bone resorption. In men, it contributes to testosterone suppression, indirectly supporting cancer regression. The formulation’s extended half-life enables consistent plasma levels, reducing peak-trough fluctuations.

Directions for Use

  • Postmenopausal Symptoms - Oral: 1–2 mg/day, typically in a 3-weeks-on, 1-week-off cycle, Patches: Vivelle-Dot (biweekly) start 0.0375–0.05 mg/day, adjust to 0.025–0.1 mg/day, Climara (weekly) begin 0.025 mg/day, titrate as needed, Gels: 0.25–1.25 mg/day applied to thigh (Divigel), Metered Pump: 0.52–0.75 mg/day on upper arm (Estrogel, Elestrin), Sprays: 1–3 sprays/day to inner forearm (Evamist, 1.53 mg/spray), Vaginal Ring: Replace every 90 days (0.05–0.1 mg/day), IM Injection: Estradiol valerate 10–20 mg every 4 weeks, Cypionate 1–5 mg every 3–4 weeks
  • Atrophic Urethritis / Vaginitis - Use oral or systemic estrogens when generalized hypoestrogenism is present, Topical preparations preferred for isolated local symptoms
  • Hypoestrogenism / Ovarian Failure - Oral: 1–2 mg/day continuously, Alternative options include transdermal patches or monthly injections (10–20 mg valerate)
  • Primary Ovarian Failure / Surgical Menopause - Long-term use recommended with cyclic or continuous regimens depending on endometrial protection
  • Osteoporosis Prevention - Oral: ≥0.5 mg/day; adjust based on patient response and risk profile, Patch: 0.025 mg/day twice-weekly or once-weekly, Menostar (low dose) 0.014 mg/day for prevention only
  • Breast Cancer (Palliative Therapy) - Oral: 10 mg 3 times/day for ≥3 months in carefully selected postmenopausal patients
  • Prostate Cancer (Palliative Use in Men) - Oral: 1–2 mg 3 times/day, IM: ≥30 mg estradiol valerate every 1–2 weeks
  • General Notes - Minimum effective dose for shortest possible duration is preferred, Add progestin in women with intact uterus to prevent endometrial hyperplasia, Monitor with regular follow-up: clinical response, endometrial status, and bone density where applicable

Storage

  • Store in a cool, dry place below 25°C. Protect from light and humidity.
  • Do not refrigerate. Keep blister packs sealed until use. Keep out of reach of children.

Possible Side Effects

  • Most common side effects include nausea, headache, breast tenderness, and bloating
  • Rare but serious risks include thromboembolic events, stroke, gallbladder disease, and hepatic dysfunction
  • In long-term therapy, especially in women with an intact uterus, endometrial surveillance is essential
  • Discontinue immediately if vision changes, chest pain, or jaundice occur

FAQs

Yes, it can be taken daily with or without breaks, depending on whether endometrial protection is co-prescribed.
Significant improvement is usually seen within 2–4 weeks of starting therapy.
Yes, it is used in male patients with advanced prostate cancer and in other hormone-modulating treatments.
With regular medical oversight and risk-benefit reassessment, long-term use can be appropriate in many cases.
Yes, under the guidance of a healthcare provider experienced in transgender medicine.

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