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Review Details
(4)
| Generic For | LUPRON |
|---|---|
| Active Ingredient | LEUPROLIDE ACETATE |
| Strength | 11.25MG |
| Manufacturer | BDR PHARMA |
| Pack Size | Price Per Unit | Unit Price | QTY | CART | Best Coupon Price MAX DISCOUNT |
|---|---|---|---|---|---|
| 1 BOX - 1 VIAL | $ 133.10 | $ 133.10 |
$ 113.13
Apply ZARVY26 (-15%)
You save $ 19.97
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| 2 BOXES - 2 VIALS | $ 135.10 | $ 270.20 |
$ 229.67
Apply ZARVY26 (-15%)
You save $ 40.53
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| ★ Best Value 3 BOXES - 3 VIALS | $ 139.67 | $ 419.00 |
$ 356.15
Apply ZARVY26 (-15%)
You save $ 62.85
|
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Bdsure 11.25 is a long-acting depot injection of leuprolide acetate 11.25mg, classified as a GnRH agonist that exerts powerful endocrine modulation. It works by persistently stimulating GnRH receptors in the hypothalamus, ultimately leading to downregulation of gonadotropin release and suppression of sex hormone production. This mechanism is central to its clinical utility in treating hormone-sensitive malignancies such as prostate cancer, as well as various gynecological and pediatric hormonal disorders. The 11.25mg dose is specifically formulated for 3-month sustained action, offering both therapeutic efficacy and reduced injection frequency in long-term hormonal regulation.
- AntiCancer Drugs > Prostate Cancer Used as first-line palliative therapy for advanced or metastatic prostate cancer. It induces a reversible chemical castration effect by reducing testosterone levels, thus slowing tumor growth and disease progression. Bdsure 11.25 provides a convenient 3-month dosing option for consistent androgen suppression. - Hormones & Menopausal Symptoms > Endometriosis Indicated for the suppression of endometrial tissue proliferation and inflammation, offering symptom relief in cases of dysmenorrhea, pelvic pain, and menstrual irregularities. Administered every 3 months, typically not exceeding a total treatment duration of 6 months. > Uterine Fibroid Used preoperatively to reduce fibroid size and bleeding, facilitating surgical intervention. Acts by limiting estrogen-driven fibroid expansion and improving hematologic stability. > Precocious Puberty Employed in pediatric endocrinology to delay early sexual development in children diagnosed with central precocious puberty. The 11.25mg 3-month depot is titrated based on age, weight, and hormonal profile to maintain suppression of premature hypothalamic-pituitary activation.
Leuprolide acetate achieves therapeutic effects through constant activation of GnRH receptors, initially triggering a hormonal flare before leading to sustained suppression of luteinizing hormone (LH) and follicle-stimulating hormone (FSH). In males, this translates to reduced testosterone; in females and children, it curtails estrogen levels and premature gonadal activation. The 11.25mg formulation ensures steady drug release over three months, improving compliance and minimizing hormonal fluctuation. Its efficacy in both oncology and reproductive health makes it a cornerstone in long-acting endocrine therapy.
Prostate Cancer (Adults): → 7.5 mg IM every 4 weeks → 22.5 mg IM every 12 weeks → 30 mg IM every 16 weeks → 45 mg IM every 24 weeks → Bdsure 11.25: 11.25 mg IM every 3 months → Other options: CAMCEVI 42 mg (q6mo), ELIGARD (7.5–45 mg) Endometriosis (Adults): → 3.75 mg IM monthly (up to 6 months) or → 11.25 mg IM every 3 months → Often co-prescribed with norethindrone to counteract hypoestrogenic effects → Max cumulative duration: 12 months Uterine Fibroid (Adults): → 3.75 mg IM monthly (max 3 months) or → 11.25 mg IM once prior to surgery → Aims to reduce fibroid volume and bleeding Central Precocious Puberty (Children ≥1 year): → ≤25 kg: 7.5 mg IM monthly → 25–37.5 kg: 11.25 mg IM monthly → >37.5 kg: 15 mg IM monthly → 11.25 or 30 mg IM every 3 months → 45 mg IM every 6 months → Subcutaneous FENSOLVI (≥2 years): 45 mg every 6 months Important Notes: → Injections must be administered intramuscularly by a trained provider → If a dose is missed, Take the missed dose as soon as possible. Do not double up. → Monitor hormonal response and symptom control routinely → Consider add-back therapy for extended treatment to reduce bone loss
Store in a cool and dry environment below 25°C. Do not freeze. Protect from direct sunlight and excessive humidity. Ensure proper handling and storage of vials prior to administration. Keep out of reach of children.
Common: hot flashes, reduced libido, injection site discomfort, night sweats, fatigue Less Common: mood swings, insomnia, headaches, bone mineral density loss Rare: serious allergic reactions, pituitary apoplexy, cardiovascular complications Seek immediate medical advice if symptoms such as persistent dizziness, chest tightness, or visual disturbances occur.
Receiving my Bdsure injection is a key part of my ongoing prostate cancer treatment. This pharmacy provides a reliable and professional service.
Finding a reliable pharmacy for my treatment was so important. Their service for my Bdsure injection has been excellent and discreet.
作为我长期治疗方案的一部分，能从这里方便地订购到博舒（Bdsure）注射剂，让我非常安心。
The team at this pharmacy is very professional. They handled my prescription with care, and the shipping was fast and private.
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