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Review Details
(28)
| Drug Type | Original |
|---|---|
| Active Ingredient | ESTRADIOL VALERATE |
| Strength | 1MG |
| Manufacturer | ZYDUS CADILA |
| Pack Size | Price Per Unit | Unit Price | QTY | CART | Best Coupon Price MAX DISCOUNT |
|---|---|---|---|---|---|
| 1 BOX - 28 TABLETS | $ 0.60 | $ 16.90 |
$ 14.36
Apply ZARVY26 (-15%)
You save $ 2.53
|
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| 2 BOXES - 56 TABLETS | $ 0.66 | $ 36.90 |
$ 31.37
Apply ZARVY26 (-15%)
You save $ 5.54
|
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| ★ Best Value 3 BOXES - 84 TABLETS | $ 0.68 | $ 56.90 |
$ 48.36
Apply ZARVY26 (-15%)
You save $ 8.54
|
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Progynova 1mg Tablet contains Estradiol Valerate, a synthetic estrogen used in various hormonal therapies. As an esterified form of estradiol, it offers improved oral bioavailability and a prolonged duration of action. This formulation is widely prescribed for postmenopausal symptom relief, hypoestrogenism management, and prevention of osteoporosis. Additionally, Progynova 1mg plays a role in complex hormonal modulation strategies for conditions like prostate cancer and breast cancer. It is also considered in selected cases for feminizing hormone therapy or menstrual cycle regulation in estrogen-deficient women.
- HORMONES & MENOPAUSAL SYMPTOMS > Menopausal Hormone Therapy Prescribed for vasomotor instability, night sweats, vaginal dryness, and other menopausal discomforts. - FEMTECH > Menstrual Control Used to stabilize hormonal fluctuations, particularly in women with irregular menses or primary ovarian insufficiency. - FEMTECH > Vaginal & Urethral Atrophy Restores tissue integrity and moisture in hypoestrogenic states leading to vaginal or urethral symptoms. - LIFESTYLE-RELATED DISEASES > Osteoporosis Helps maintain bone mineral density in postmenopausal women at risk of fracture. - DISEASES/SYMPTOMS > Hypoestrogenism Used in ovarian failure, post-oophorectomy states, or adolescent hypogonadism to normalize estrogen levels. - AntiCancer Drugs > Prostate Cancer Used in male patients for testosterone suppression as part of palliative hormone therapy. - AntiCancer Drugs > Breast Cancer Off-label use in older women or select palliative cases for estrogen-receptor modulation. - AntiCancer Drugs > Others (for off-label hormonal modulation) Used in gender-affirming hormone therapy and rare endocrine disorders requiring estrogen repletion.
Estradiol Valerate is hydrolyzed in the body to release bioidentical estradiol. It mimics the function of endogenous estrogen and binds to estrogen receptors in various tissues, helping alleviate systemic and local symptoms of estrogen deficiency. When used consistently, it supports vascular stability, maintains bone density, and improves urogenital tissue health. In cancer-related indications, high doses suppress gonadotropins and endogenous sex hormone production. In transgender care, it is used as a feminizing agent in hormone therapy regimens.
1. Postmenopausal Symptoms (e.g., vasomotor) - Oral: 1–2 mg daily in a cyclic regimen (3 weeks on, 1 week off) - Transdermal Patch: - Twice-weekly: 0.0375–0.05 mg/day initially; adjust to 0.025–0.1 mg/day - Once-weekly: 0.025 mg/day initially; titrate up to 0.1 mg/day - Gel (Divigel): 0.25–1.25 mg/day applied to upper thigh - Pump (Estrogel/Elestrin): 0.52–0.75 mg/day to upper arm - Spray (Evamist): 1.53 mg per spray; apply 1–3 sprays to forearm - Vaginal Ring (Femring): Insert once every 90 days (0.05 or 0.1 mg/day) - IM Injection: - Estradiol cypionate: 1–5 mg every 3–4 weeks - Estradiol valerate: 10–20 mg every 4 weeks 2. Atrophic Urethritis / Vaginitis - Oral or topical therapy preferred depending on symptom severity - Localized estrogen therapy recommended when possible 3. Hypoestrogenism / Ovarian Failure / Oophorectomy - Oral: 1–2 mg daily - IM: - Valerate: 10–20 mg every 4 weeks - Cypionate: 1.5–2 mg monthly 4. Osteoporosis Prevention - Oral: Minimum 0.5 mg/day; clinical dose may vary - Transdermal: - Twice-weekly: 0.025 mg/day - Once-weekly: 0.025 mg/day - Ultra-low dose patch (Menostar): 0.014 mg/day 5. Breast Cancer (Palliation) - Oral: 10 mg three times daily for at least 3 months 6. Prostate Cancer (Palliation) - Oral: 1–2 mg three times daily - IM (Valerate): 30 mg or more every 1–2 weeks General Recommendations: - Always use lowest effective dose for shortest appropriate duration - Add progestin if uterus is intact to reduce endometrial cancer risk - Periodic reassessment (every 3–6 months) is advised
Store below 25°C in a dry place, away from moisture and direct light. Keep in original packaging. Do not refrigerate. Keep out of reach of children.
Frequent side effects include nausea, breast tenderness, headache, and mild fluid retention. Long-term use may increase risks of thromboembolism, endometrial hyperplasia, or gallbladder disease. Serious adverse events are rare but should be monitored, especially in those with cardiovascular or hepatic risk factors.
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I was prescribed Progynova for menopausal symptoms and was looking for a cost-effective option. I was hesitant to buy online but found their website incredibly informative. They provided extensive details about the medication, its uses, and manufacturer information, which made me feel secure. The ordering process was simple, and my package arrived discreetly. For anyone feeling anxious about ordering online, this site’s transparency is a huge plus.
The price for Progynova here is much better than at other places I've looked. It helps manage my expenses.
No issues with shipping, my order was well-protected and arrived on time.
No combo deals available at the moment.
