Xigduo XR 10/1000mg, Dapagliflozin + Metformin, High-Dose Extended-Release, Type 2 Diabetes Dual Therapy, Heart & Kidney Protection, Online Pharmacy
DIABETES BEAUTY Liver Health Cardiovascular Diseases Metformin DIET +10

Xigduo XR 10/1000mg

★★★★★
★★★★★
4.9

(8)

Drug Type Original
Active Ingredient DAPAGLIFLOZIN|METFORMIN
Strength 10MG|1000MG
Manufacturer ASTRAZENECA
Xigduo XR 10/1000mg tablets box (Dapagliflozin 10mg + Metformin 1000mg ER) angled front view
Xigduo XR 10/1000mg tablets white box back side with prescribing and dosage information
Xigduo XR 10/1000mg tablets multiple blister packs stacked, showing silver strips and labeling
Xigduo XR 10/1000mg tablets box (Dapagliflozin 10mg + Metformin 1000mg ER) angled front view
Xigduo XR 10/1000mg tablets white box back side with prescribing and dosage information
Xigduo XR 10/1000mg tablets multiple blister packs stacked, showing silver strips and labeling
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Product Description

Xigduo XR 10/1000mg is an original branded medication developed by AstraZeneca for the management of Type 2 diabetes. It combines Dapagliflozin 10mg, an SGLT-2 inhibitor, and Metformin 1000mg, a first-line diabetes treatment, in an extended-release (XR) formulation. This dual-action therapy lowers blood sugar levels by enhancing insulin sensitivity, reducing glucose production in the liver, and increasing glucose excretion through urine. The XR formulation ensures gradual absorption, minimizing gastrointestinal side effects commonly associated with Metformin.

Indications & Uses

- First-Line Diabetes Treatment: Metformin enhances insulin sensitivity and reduces glucose production in the liver. - Blood Sugar Regulation: Dapagliflozin helps remove excess glucose through urine by blocking its reabsorption in the kidneys. - Weight Management Support: Aids glycemic control while promoting potential weight reduction. - Cardiovascular Benefits: Dapagliflozin may help lower the risk of heart failure and cardiovascular complications. - Liver Health Support: May contribute to managing non-alcoholic fatty liver disease (NAFLD).

Benefits & Effectiveness

Xigduo XR 10/1000mg works through a dual mechanism: - Metformin (First-Line Therapy) reduces glucose production in the liver and enhances insulin sensitivity. - Dapagliflozin (SGLT-2 Inhibitor) blocks glucose reabsorption in the kidneys, leading to increased glucose excretion and improved blood sugar control. - The extended-release formulation ensures gradual absorption of Metformin, reducing gastrointestinal side effects and providing long-lasting blood sugar control.

Directions for Use

- Take one tablet (10mg/1000mg) once daily, preferably with the first meal of the day. - Swallow the tablet whole—do not crush or chew, as it is an extended-release (XR) formulation. - Helps regulate blood sugar levels, supporting long-term metabolic health. - Maintain proper hydration, as increased urination is a common effect due to SGLT-2 inhibition.

Storage

- Store in a cool, dry place, away from direct sunlight, heat, and moisture. - Keep the tablets in their original packaging to maintain potency. - Ensure the medication is out of reach of children and pets.

Possible Side Effects

While generally well-tolerated, some users may experience mild side effects such as: - Increased urination and thirst (due to Dapagliflozin) - Mild dehydration or dizziness - Gastrointestinal discomfort, nausea, or diarrhea (due to Metformin) - Urinary tract infections (UTIs) and genital yeast infections - Low blood sugar when taken with other diabetes medications Important: Pregnant women should consult their doctor before handling or using this medication. If severe side effects occur, such as lactic acidosis or ketoacidosis, seek medical attention immediately.

FAQs

Xigduo XR 10/1000mg is an original branded medication developed by AstraZeneca for the treatment of Type 2 diabetes. It contains Dapagliflozin, an SGLT-2 inhibitor that enhances glucose excretion through urine, and Metformin, a first-line diabetes treatment that improves insulin sensitivity and lowers glucose production in the liver. The extended-release (XR) formulation ensures gradual absorption of Metformin, minimizing gastrointestinal side effects while providing sustained blood sugar control.
Xigduo XR 10/1000mg functions through two key mechanisms: Dapagliflozin (SGLT-2 Inhibitor) blocks glucose reabsorption in the kidneys, leading to increased glucose excretion and lower blood sugar levels. Metformin (First-Line Therapy) reduces glucose production in the liver and improves insulin sensitivity. The extended-release (XR) formulation allows for gradual absorption, improving metabolic health while minimizing gastrointestinal discomfort.
Common side effects may include increased urination, mild dehydration, dizziness, nausea, diarrhea, urinary tract infections (UTIs), and genital yeast infections. These effects are usually mild and temporary.
Take one tablet (10mg/1000mg) once daily, preferably with your first meal of the day. Swallow the tablet whole—do not crush or chew, as it is an extended-release (XR) formulation. Stay hydrated, as increased urination is a common effect.
Store Xigduo XR 10/1000mg in a cool, dry place, away from direct sunlight and moisture. Keep it in its original packaging and ensure it’s out of reach of children and pets.
This medication is not recommended for individuals with severe kidney disease, Type 1 diabetes, or a history of lactic acidosis. Pregnant or breastfeeding women should consult their doctor before use.

Ratings & Reviews

Reviewed by 8 Users

4.9/5
★★★★★
★★★★★
5★
88%
4★
13%
3★
0%
2★
0%
1★
0%

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B**n R**a Jun 25, 2023
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Tags helped narrow itdown

Filtered by dose and this popped up right away.

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A*a C**l Mar 11, 2023
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Fast delivery with tracking

Tracking number worked and arrived a day early.

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H**y C**n Jan 17, 2023
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Credit applied without issue

Used a referral code and the discount showed up right away.

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D**l M**s Oct 05, 2022
★★★★★
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Ordering again after 6 months

Reordered after trying it before. Site’s still smooth.

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E**h R**n Aug 28, 2022
★★★★★
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Professional packaging

No dents, labels clean, and safety seal intact.

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