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(76)
| Generic For | LIPITOR |
|---|---|
| Active Ingredient | ATORVASTATIN |
| Strength | 20MG |
| Manufacturer | LUPIN |
| Pack Size | Price Per Unit | Unit Price | QTY | CART | Best Coupon Price MAX DISCOUNT |
|---|---|---|---|---|---|
| 1 BOX - 150 TABLETS | $ 0.38 | $ 57.70 |
$ 49.05
Apply ZARVY26 (-15%)
You save $ 8.66
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| 2 BOXES - 300 TABLETS | $ 0.37 |
3% $ 115.40
$ 112.10
|
$ 95.29
Apply ZARVY26 (-15%)
You save $ 16.82
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| ★ Best Value 3 BOXES - 450 TABLETS | $ 0.38 |
1% $ 173.10
$ 171.10
|
$ 145.44
Apply ZARVY26 (-15%)
You save $ 25.67
|
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Tonact 20 is a generic formulation of atorvastatin 20mg, a high-potency statin widely used for the treatment of dyslipidemia and the prevention of cardiovascular events. It belongs to the HMG-CoA reductase inhibitor class, working by decreasing hepatic cholesterol synthesis and increasing LDL receptor expression. The 20mg dose is considered moderate to high intensity and is often prescribed for patients with significant cardiovascular risk factors or those requiring substantial LDL-C reduction. It is suitable for both primary and secondary prevention strategies and is often part of long-term treatment plans.
- Lifestyle-related Diseases > Hyperlipidemia Effective in lowering elevated LDL cholesterol, total cholesterol, and triglycerides, while modestly increasing HDL cholesterol. Prescribed for primary hypercholesterolemia, mixed dyslipidemia, and severe hypertriglyceridemia. Also indicated for familial lipid disorders such as Type III dyslipidemia and heterozygous familial hypercholesterolemia. > Cardiovascular Diseases Used to prevent atherosclerotic cardiovascular disease (ASCVD), including heart attacks, stroke, and coronary revascularization. Particularly recommended for patients with type 2 diabetes, chronic kidney disease, metabolic syndrome, or history of coronary artery disease. > Cerebral Infarction & Myocardial Infarction Reduces the risk of ischemic events by stabilizing plaques, lowering systemic inflammation, and improving endothelial function. Plays a key role in both primary and secondary prevention of stroke and myocardial infarction.
Atorvastatin 20mg reduces cholesterol levels by inhibiting HMG-CoA reductase, leading to decreased intrahepatic cholesterol synthesis and increased clearance of LDL-C. It also reduces VLDL synthesis and triglyceride levels. Its pleiotropic effects include reduced CRP levels, improved endothelial function, decreased oxidative stress, and plaque stabilization. These mechanisms contribute to substantial cardiovascular protection, particularly in high-risk populations.
General Hyperlipidemia / HeFH / Type III Dyslipidemia / Hypertriglyceridemia: - Starting dose: 10–20 mg once daily - Maintenance dose: 10–80 mg once daily - For aggressive LDL-C reduction (>45%), consider starting at 40 mg/day - Should be used along with a diet low in saturated fats and cholesterol Homozygous Familial Hypercholesterolemia (HoFH): - Adult dose: 10–80 mg once daily - Pediatric (≥10 years): 10–80 mg once daily - May be combined with LDL apheresis to enhance efficacy Heterozygous Familial Hypercholesterolemia (HeFH): - Adults: 10–80 mg once daily - Children (≥10 years): 10–20 mg once daily - Lipid levels should be reassessed every 4–6 weeks Cardiovascular Disease Prevention (Primary & Secondary): - Starting dose: 10–20 mg once daily - Maintenance dose: 10–80 mg once daily - Shown to significantly reduce the risk of MI, stroke, angina, and need for revascularization - Especially beneficial in T2DM patients and elderly individuals with multiple cardiovascular risk factors
Store below 30°C in a dry place, away from moisture and direct sunlight. Do not remove tablets from the blister until administration. Keep out of reach of children.
Common: muscle soreness, fatigue, nausea, diarrhea, headache Occasional: increased liver enzymes, mild insomnia, dizziness Rare: rhabdomyolysis, memory impairment, liver dysfunction Seek medical advice immediately if muscle weakness, dark urine, or jaundice occurs.
No damage and fully sealed.
Delivered 2 days ahead of schedule.
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