Dicaris Adults, Levamisole, Antiparasitics, Antibiotics & Infections, ZarvyPharm
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ANTIBIOTICS ANTIPARASITICS Anthelmintics Skin/Soft Tissue Infection

Dicaris Adults Tablet

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Generic For ERGAMISOL
Active Ingredient LEVAMISOLE
Strength 150MG
Manufacturer JANSSEN PHARMACEUTICALS
Dicaris Adults 30 tablets box, front-facing view with product name visible
Close-up of Dicaris Adults blister information, dosage and label readable
Dicaris Adults 30 tablets box, angled packaging shot showing side and front
Dicaris Adults 30 tablets box, front-facing view with product name visible
Close-up of Dicaris Adults blister information, dosage and label readable
Dicaris Adults 30 tablets box, angled packaging shot showing side and front
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Product Description

Dicaris Adults – 30 Tablets contains levamisole, an imidazothiazole derivative and well-known anthelmintic used to treat intestinal nematode infections such as ascariasis (roundworm), hookworm, and mixed soil-transmitted helminths (STH). Its mechanism involves selective agonism at parasite nicotinic acetylcholine receptors, inducing spastic paralysis and facilitating worm expulsion via natural peristalsis.
Beyond antiparasitic activity, levamisole has immunomodulatory effects, previously applied off-label in pediatric nephrotic syndrome and as an adjunct in post-surgical colorectal cancer (Duke’s C stage). Experimental dermatological roles have included adjunctive therapy for skin and soft tissue infections (SSTIs).
Due to risks such as agranulocytosis and vasculitis, many non-anthelmintic indications are now restricted. Still, Dicaris remains a trusted choice in the Antiparasitics category and is available through a reliable online pharmacy, occasionally referenced in Antibiotics & Infections contexts when immune modulation intersects with infection management.

Indications & Uses

  • Ascariasis / Hookworm / Trichuris: Dicaris Adults (Levamisole 150mg) is indicated as a first-line oral treatment for adult patients with intestinal helminthiasis.
  • Mixed Soil-Transmitted Helminths (STH): Widely used for management of multiple intestinal parasites in single-dose therapy.
  • Skin and Soft Tissue Infections (experimental): Levamisole has been investigated as an adjunct in immune-related or parasite-associated SSTIs, though this remains off-label and primarily in research contexts.

Benefits & Effectiveness

  • Rapid nematode expulsion via neuromuscular paralysis.
  • High cure rates for ascariasis and hookworm with single-dose therapy.
  • Immunostimulatory activity: enhances T-cell response and macrophage function.
  • Off-label benefit in steroid-dependent nephrotic syndrome by lowering relapse frequency.
  • Historical adjunct in cancer adjuvant therapy to improve immune surveillance.

Directions for Use

  • Ascariasis (Roundworm): Adults 120–150 mg orally after a light meal (single dose).
  • Hookworm / Mixed STH: Adults 2.5 mg/kg single dose; repeat after 7 days if severe.
  • Pediatrics: <12 years – 2.5–3 mg/kg single dose; 12–18 years – 150 mg single dose.
  • Nephrotic Syndrome (off-label, pediatric): 2–2.5 mg/kg every other day for 12–24 months (CBC monitoring required).
  • Colon Cancer Adjunct (off-label): 50 mg orally every 8h × 3 days, repeated every 2 weeks with 5-FU chemotherapy.
  • Method: Administer orally with water after meals; no fasting or laxatives required.
  • Contraindications: Hypersensitivity, agranulocytosis history, severe blood dyscrasias, pregnancy unless benefits outweigh risks.

Storage

  • Store below 30 °C, protected from moisture and direct sunlight.
  • Keep container tightly closed until use.
  • Store out of reach of children.

Possible Side Effects

  • Common: nausea, abdominal pain, metallic taste, fatigue.
  • Moderate: headache, dizziness, mild rash.
  • Serious: agranulocytosis, vasculitis, encephalopathy, seizures. Immediate medical attention required if severe effects occur.

FAQs

It is best taken after a light meal to minimize gastrointestinal upset.
Only in severe or persistent infections; typically repeated after 7 days.
For its immune-boosting effect, potentially enhancing the body’s ability to fight residual cancer cells.
Regular blood counts to detect early signs of agranulocytosis.
Its use has been restricted in some countries due to toxicity risks, but it remains available for anthelmintic use in others.

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