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Review Details
(5)
| Generic For | N/A |
|---|---|
| Active Ingredient | SODIUM VALPROATE|VALPROIC ACID |
| Strength | 200MG|87MG |
| Manufacturer | SUN PHARMA |
| Pack Size | Price Per Unit | Unit Price | QTY | CART | Best Coupon Price MAX DISCOUNT |
|---|---|---|---|---|---|
| 1 BOX - 100 TABLETS | $ 0.39 | $ 38.80 |
$ 32.98
Apply ZARVY26 (-15%)
You save $ 5.82
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| 2 BOXES - 200 TABLETS | $ 0.32 |
18% $ 77.60
$ 63.90
|
$ 54.32
Apply ZARVY26 (-15%)
You save $ 9.59
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| ★ Best Value 3 BOXES - 300 TABLETS | $ 0.30 |
22% $ 116.40
$ 90.60
|
$ 77.01
Apply ZARVY26 (-15%)
You save $ 13.59
|
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Encorate Chrono 300 is a dual-action controlled-release formulation that combines 200mg of sodium valproate and 87mg of valproic acid. This balanced blend delivers consistent therapeutic levels over time, providing effective control of seizures, mood disorders, and migraine recurrence. It is particularly suitable for patients requiring stable plasma concentrations with fewer daily doses.
- Sleep & Mental Health > Epilepsy Encorate Chrono 300 effectively treats various types of epilepsy, including complex partial seizures, generalized tonic-clonic seizures, and absence seizures. It enhances GABA activity to calm excessive electrical discharges in the brain. > Bipolar Disorder It helps stabilize mood swings in patients with bipolar disorder, providing therapeutic benefits in both acute mania and maintenance phases. Often used in conjunction with or as an alternative to lithium. > Depression, Anxiety, PTSD While not a first-line agent, Encorate Chrono 300 may be prescribed as an adjunct mood stabilizer in treatment-resistant depression, anxiety disorders, and PTSD, especially when impulsivity or emotional dysregulation are present. - Painkillers & Headache > Migraine Prevention This formulation is frequently used for preventing episodic migraines, working by reducing cortical excitability and abnormal neural signaling pathways associated with chronic headaches.
Encorate Chrono 300 exerts antiepileptic and mood-stabilizing effects by enhancing inhibitory neurotransmission via GABA and reducing repetitive neuronal firing. The combination of sodium valproate and valproic acid ensures more consistent blood levels with extended action, resulting in reduced dosing frequency and improved adherence.
Adult Dosing - Initial: 10–15 mg/kg/day in 1–2 divided doses with food - Titration: Increase by 5–10 mg/kg weekly - Maintenance: 20–30 mg/kg/day (~1200–1800 mg/day) - Max: 60 mg/kg/day (~3600 mg/day for 60 kg adult) - Notes: Divide doses >250 mg/day; monitor liver enzymes and valproate levels regularly Pediatric Dosing (10+ years) - Initial: 10–15 mg/kg/day with food - Titration: Weekly increments of 5–10 mg/kg - Maintenance: Most stabilize at 20–30 mg/kg/day - Max: 60 mg/kg/day - Notes: Monitor liver and platelet count; adjust dose for seizure type and clinical response Special Considerations - Tapering from other AEDs: Reduce by 25% every 2 weeks - Do not substitute with single-compound products due to bioavailability differences - Long half-life supports once-daily dosing - Plasma monitoring target: 50–100 mcg/mL - Essential labs: AST, ALT, platelet count, ammonia (if symptomatic), drug level
Store Encorate Chrono 300 in a dry place below 30°C, away from moisture and direct sunlight. Keep in original packaging and out of reach of children. Do not use tablets that appear damaged or discolored.
- Common: Drowsiness, tremor, nausea, dizziness, weight gain - Serious: Liver toxicity, pancreatitis, blood dyscrasias, hyperammonemia - Psychiatric: Irritability, confusion, mood instability - Hormonal: Menstrual irregularity, PCOS (in females) - Long-term monitoring: Liver function tests, CBC, and valproate serum levels
My doctor increased my Encorate Chrono to 300mg. Reordering from this site was easy and the shipment was fast.
For a medication I rely on daily, I need a source I can trust. Their service is always professional and discreet.
So glad I have a pharmacy that ships to Canada without hassle. Their service for my Encorate Chrono has been perfect.
I've been on this medication for a while, and this pharmacy has been consistently reliable for my prescription needs.
This medication is essential for me, and this pharmacy's reliable service makes managing my health much less stressful.
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